How you react is very variable. But the first two or three weeks will probably establish a pattern and that will help you plan. But till then, one day at a time. Good to have someone with you first time. You may like to have company or not throughout (I was happy on my own), and a port is worth discussing, especially if your veins are uncooperative. These choices are up to you entirely. You will be asked lots of questions before each treatment - always good to answer these honestly. It's not an exam, there are no right answers, knowing exactly how you are going will help your oncology nurses know if you need help with digestion, fatigue or anything else that may crop up. Best wishes