Hi Sue....I couldn't have Tamoxifen for the same reason as you (blood clot issues). As I have brain aneurysms Tamoxifen could cause problems with clotting and my oncologist was not going to take that chance. I'm about to have my 2nd Zoladex injection and can tell you to numb the area where it is going (normally stomach fat) prior to getting the injection as it does hurt! It's a VERY large needle! I am lucky to have a daughter and daughter-in-law to be as Registered Nurses so can get it done at home each month. A nurse told me last week that you can just numb it with a cold pack for around 10 minutes prior to the injection but think you can get numbing patches too from the chemist. Jan
