Dear @alisonzagar
I took Letrozole for ten years. In context, my bone density was excellent when I started and it was strongly recommended, first for five years but after four my oncologist was influenced by research that showed ten years would give a better outcome. My bone density has declined during that time - how much is Letrozole and how much age (I was 67
when I started on Letrozole) is pretty hard to tell. It is possible to have treatment such as Prolia to strengthen bone density but there are some side effects and implications if you go down that path. I’ve avoided that so far - my next bone density test may indicate whether there is any hiatus in the bone loss (I have been off Letrozole for nine months) or if I may need to consider other treatment. On the positive side I have never had any aches or joint pain, or weight gain. All I can recommend is give it a shot. You will know within a few months what side effects, if any, you have and can make a more informed decision then. As for the stats, it all depends which side of the ledger we are on, doesn’t it? And we don’t know that. I opted for doing all I could and I don’t regret it but it’s a really personal decision and you should weigh up all the factors particular to you. Best wishes whatever you decide,