Hi @duxx1234, my onc prescribed just as yours is. Dex is a steroid and will help prevent reactions to your chemo and help with nausea. It's like 'pumped up' Prednisone. I found it just made me feel a little wide eyed, energy twitchy but you'll find your body does get used to it as well. Have you got a breast care nurse? She might be able to give you some literature to read. I found being able to wholly trust in my oncologist really helped. I found her wonderful and she never overwhelmed me with too much info. I got a very measured amount which is great as it's all so overwhelming. Xxoo