Janey,I don't see why you couldn't,but we are all different,and our doctors know best you would hope;)My onc just explained it by saying that the Aromatase Inhibitors have such harsh side effects with the joint problems etc.She said if you can take Tamoxifen for a couple of years,you won't have that problem and the risk of endometrial cancer after two years is negligible.Then you change.For me,the idea of postponing joint problems is a good one,because at my age I feel that once all that stuff starts it is going to age me even more!!!!I have always been a reasonably fit person,so for the next two years I am going to work even harder at maintaining that,so when I do change to one of the AI drugs,hopefully my body will have a fighting chance!!!lol. stand by for the next chapter!!!! I would be interested to hear what your onc says Janey.Hope you are doing ok Janey,and still sitting on that verandah out of harms way!! Cheers Robyn.