Hi Michelle,Christine,and Louise,Here is another spin on this topic.I am 58 and have been in Menopause for 6years.My chemo is finishing soon,and my oncologist,who I really admire,has been talking to me about this subject.I will be going onto Tamoxifen for 2years and then switching to an Aromatase Inhibitor for 5,then we will review things,and maybe continue for another 5.The reasoning for this is,that the benefits of Tamoxifen are well known,but also the increased risks with it long term.Of course,AI drugs have the effects on the bones in post menopausal women.So I guess you could say,the best of both,but hopefully avoid the risk of endometrial cancer by using Tamoxifen for only 2 years.My bones are particularly good,and in that. 2 years,I will be working hard at keeping them that way.Hope that this may help,but it probably adds to the confusion.;)Cheers. Robyn.xoxo