Hi ladylace. I changed from tamoxifen to Anastrazole nine months ago. I feel better on this one. Yes the muscle and bone pain is awful but I manage that with panadol Osteo magnesium vit d and calcium. Dryness is another prob to continuously manage. Dry eyes mouth skin vagina. Apart from the physical side effects I am me on Anastrazole compared to Tamoxifen which made me mentally foggy. Happy to answer any other questions. Good luck
Janine xo