My symptoms were mild until month 6 when the knees and shoulders really hurt. Sleepless/ restless nights seem to be connected. I plan to stick to a big exercise program to see if it helps but will stop if it really alters my quality of life. My oncologist told us that the risk of recurrence is reduced by only a few percent in many cases so I will check with him in January. I wonder if having a break for a few weeks has any benefits or disadvantages.