The other issue with AI's is how they affect your body. We know that they have a negative effect on bone density, so there's a bit of a risk benefit ratio thing happening. Do they want to keep us on AI's with the risk of a population of osteopaenic or osteoporotic women. I've said women quite deliberately there, as men tend to be put on tamoxifen, as their hormonal profile is quite different. Tamoxifen seems to have a bit of a protective effect on bone density, or at worst, no effect