Chemo is a ‘sweeper’ of the body - it’s job is to kill any cancer cells that are circulating. Surgery and radiotherapy are targeted, they affect specific parts of the body. But chemo affects all of the body. Which is why it can be unpleasant. Reactions to chemo vary a lot. Some people have very strong reactions, including nausea and fatigue, others (like me) fairly mild reactions and it’s almost impossible to know which, until you start. Hair loss (temporary) however is common. Your oncologist is best placed to advise on how significant chemo might be but the choice is yours. Chemo isn’t a lot of fun but you will have the knowledge that you have done everything possible to avoid a recurrence. Best wishes.