I lost about 10 kilos during chemo. Was never sick but lost my taste buds on taxol, and that really has an impact when everything tastes of cardboard! I put back a bit after I finished chemo, but have worked hard to get back to and keep at my post chemo weight as it's better and I feel much fitter. Staff monitored my weight loss but were satisfied there was nothing amiss, blood tests etc were all fine. There has to be some pluses out of chemo, losing a bit of weight was good for me!!