Yes,some do gain weight,and some lose it.I spoke to my doctor about this,as I have always watched my weight,and worried about putting it on.I think you will find that the weight fluctuation is more to do with the fact that while you are going through chemo,you not only feel fatigued,therefore can't exercise (even just walking) as usual,but you also don't always feel like eating the right foods.My oncologist asked me at my first visit if I exercised.I told her that I walked every day,and her reply was,"DONT STOP".I walked every day through treatment,even when I found it hard.I finished my chemo 2 weeks ago,and I haven't put on any weight at all.However,everyone is different,and some people struggle through chemo.I had the same chemo treatment as you are having,so I hope you find it as I did.All the best,and feel free to ask more questions if we can help.xoxo. Robyn