Vaginal atrophy. Why didn't someone warn me?
There’s a long list of things nobody warns you about when you go through cancer treatment. It is fairly well known that chemotherapy, radiation therapy and significant surgery all carry risks and sid...
Forum Discussion
Some warnings about Xylocaine:
Warning:
Excessive dosage, or short intervals between doses, can result in high levels of lignocaine or its metabolites and serious adverse effects. Patients should be instructed to strictly adhere to the recommended dosage and administration guidelines (the management of serious adverse reactions may require the use of resuscitative equipment, oxygen and other resuscitative drugs).
The lowest dose that results in effective anaesthesia should be used to avoid high plasma levels and serious adverse effects. Tolerance to elevated blood levels varies with the status of the patient.
Dose reduction
Debilitated, elderly and/or acutely ill patients and children should be given reduced doses commensurate with their age and physical status.
Excessive absorption
Absorption from wound surfaces and mucous membranes is relatively high, especially in the bronchial tree. Because of the possibility of significant systemic absorption, Xylocaine Jelly should be used with caution in patients with traumatised mucosa and/or sepsis in the region of the proposed application.
If the dose or site of administration is likely to result in high blood levels, lignocaine, in common with other local anaesthetics, should be used with caution in patients with epilepsy, impaired cardiac conduction, bradycardia, impaired hepatic function, severe shock and patients with severe renal dysfunction.