I've been on tamoxifen nearly 5 months. I find it hard to be sure about what symptoms to attribute to tamoxifen. The only things I think it definitely causes for me are mild hot flushes (mainly at night) and it's stopped my periods. (I'm 47). My periods did stop during chemo too but started again afterwards.Sometimes I wonder whether it disrupts my sleep. I often wake up very early (4.30-5.00) or have trouble getting to sleep even though I'm tired. I find I have to be very careful to minimise my caffeine intake, especially in the second half of the day. Or if I have a large meal later in the evening or drink alcohol I'm more more likely to struggle with sleeping. It's like any little change of routine in what I eat or drink will lead to a sleeping issue. But on the other hand, I've had problems with sleeping in the past (but usually only when stressed and I'm not stressed now).I haven't gained weight like a lot of women say they do but I've also been very careful to watch what I eat and I do quite a lot of exercise. I find it nearly impossible to lose weight, but again, I had that problem before tamoxifen.I do think it might have reduced my libido a little bit too.I hate taking a drug like this everyday to be honest, but I'm too scared not to take it. Just hope it does what it's supposed to do. Good luck with it. I hope it doesn't cause you any major problems. Janet.