Hiya. I've been on letrozole about 14 months now. Initially I had painful wrists and ankles but that has lessened. The odd day it's bad (and when I swim with just a kickboard my ankles kill me)
Initially my libido plummeted and the nether-region was teribbley dry. However my body seems to have adapted a bit. Only need lubricant now for the marital business and not all the time. Libido is back somewhat but of course not what it was pre menopause anyway. For some bizarre reason when fitter and have aching muscles I'm more interested... maybe its all the pain stimuli....haha. My post chemo and pre letrozole bone density scan showed a dranatic drop. However 12 months on and I'm within normal bone loss and possibly even gained some back in hips. I'm now doing weights to try to increase my back bone density. Next test 2 years. I haven't had any more hot flushes than I had post menopause but have a fan handy just in case. Wine, coffee and cooking always results in a hot flush but I persist regardless. Kath x