Hi Everyone

Like you,I had a lumpectomy,full node clearance,followed by radiation back in 2003.There is an 8%risk that cancer can come back despite radiation.So really 92%odds of a cure or making it to 10 yrs is good.My cancer was eostrogen +ve(both times)and I was initially put on Tamoxifen.I was 47 at the time and it really didn't agree with me-heavy period,hot flushes,bad headaches,bad mood.I persevered for 10wks but couldn't stand it.I tried the other 2 drugs you mentioned but they had similar effects.So I did my research and decided to take something natural- flaxseed tablets.I was fine for about 6 years and then I broke my ankle and had a series of operations and botch ups.I had stopped taking flaxseed and I was under a lot of stress.Then cancer came back in the same breast,same spot. I am now on Tamoxifen and it seems to be agreeing with me this time round.That's probably cos I am older and through menopause.I still get some hot flushes but take endep to help.Tamoxifen is the drug which has been around the longest compared to Femara and Arimidex.You will usually be prescribed Tamoxifen unless you are more than 2 years past meopause in which case you might have one of the others- that's what my oncologist told me anyway.Other doctors may say otherwise. Gay you can only try the drug that your doctor has recommended and see how it goes-you might feel fine.However,I don't agree with taking a drug that makes me feel dreadful.I had a friend on Tamoxifen and she had no side effects whatsoever.Then I had another friend who was miserable on it for 2 years and her cancer came back anyway.At the end of the day it's your body and your decision and if only we had a crystal ball.But your doctor should be able to answer all your questions about these drugs,then you can make an informed decision.Good luck.

                                                Tonya xx