The trials for TNBC are for women with metastatic disease. I believe the regime ACT is the current treatment standard for your Mum's diagnosis and stage. You could seek a second opinion which might give you some reassurance and even discuss concerns with your Mum's breast care nurse as they are a wealth of info. We all hope we are doing the best we can and it is confusing why we are given different chemo regimes. Know that oncologist base their decisions on years of clinical trials and statistics to know which is the best option for your Mum. Best of luck. Kath x