Hi @Jemmy
Similar to your mum, I had surgery and radiotherapy, and am now on hormone blockers. Of all my meds, the zometa is the least worrisome in terms of side effects. Although I am somewhat younger than your mum (55), as I've read on this forum since I joined, everyone's experience with meds is just so different. Can she give it a go and see how she feels? Is her bone health otherwise OK? Can your BC nurse provide any help? If you search zometa on this forum, I'm sure that there will be a bunch of comments too of people who are considering or already taking this drug. Absolute best wishes to you and your mum - she's so lucky to have you with her during the tricky decisions.
Kx