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Participate in research aimed at relieving hot flushes and night sweats

Giovanna_BCNAGiovanna_BCNA Member Posts: 1,839
edited April 2020 in General discussion

Participate in research aimed at relieving hot flushes and night sweats experienced by women after breast cancer.

Researchers across several states in Australia are conducting a study to evaluate a potential new treatment aimed at relieving hot flushes and night sweats in women diagnosed with breast cancer who are taking hormone blocking therapy (either tamoxifen or an aromatase inhibitor). 

While clinical trials have found hormone blocking therapy can significantly reduce the risk of breast cancer coming back (recurring), many women experience menopausal-like symptoms when taking hormone-blocking therapy. While these side effects are mild for many women or lessen over time, some women experience significant symptoms which can be difficult to cope with.
The study will determine whether QUE 122 (a small molecule which was found to lessen hot flushes and night sweats in an earlier study) is effective in reducing night sweats and hot flushes in women affected by breast cancer being treated with hormone blocking therapy.
You may be eligible to participate if you are:

  • Aged 18 to 70 years
  • Are taking tamoxifen or an aromatase inhibitor (i.e. anastrozole (Arimidex), letrozole (Femara) or exemestane (Aromasin).
  • Are experiencing 7 or more hot flushes/night sweats each day/evening.
  • Are able to attend 6 study visits at the research site over approximately 9 weeks.

This study is taking place at sites in Melbourne, Sydney, Adelaide, Brisbane and Perth. 

 If you are interested in participating or would like further information, please contact the study site closest to you



  • Katy_SodapopKaty_Sodapop Member Posts: 50
    I did this trial, it wasn't too annoying and I feel like if I can help for future BC warriors then I'm all in 
  • kmakmkmakm MelbourneMember Posts: 7,974
    I did it as well. I had to travel quite a distance but I really want to help so I didn'tvmind. It was a double blind trial and I was definitely on the drug as when I stopped my hot flushes got a lot worse. As soon as this drug hits the market the better as far as I'm concerned.
  • suburbangirlsuburbangirl Perth, Western AustraliaMember Posts: 123
    That's great @kmakm, thanks to you and others who help with these trials.
    I also struggle with hot flushes, are you allowed to say the name of the drug and do you know how we might hear when it is available?
  • kmakmkmakm MelbourneMember Posts: 7,974
    @suburbangirl I can't say because I don't know! It was just the QUE122 trial. I think it's run out of the USA. The research assistant didn't know what was happening next. Though she did speculate that they might trial a different dosage.

    Just have to keep our fingers crossed that it all works out and the drug makes it to market. K xox
  • Blossom1961Blossom1961 Regional VictoriaMember Posts: 2,012
    If you google QUE122 oncology it gives you the info.

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