In regards to second options- its also important to ask if your case has been to a multi disciplinary team meeting for review. Most major hospitals have a team meeting with nurses, oncologist, radiotherapist, surgeons,senior pathologists etc, and if there is any uncertainty about the course of action for a particular case, then they bring it to the meeting to discuss and review from different viewpoints before they tell the patient the treatment plan. I , and many others, found that very reassuring as a patient to know that multiple doctors had had input on my recommend treatment plan.Plus if/when things change as often happens with side effects and other things that cause a treatment plan to change, that forum is available to the doctors. Plus we all have the benfit of the 100s and 1000s of women who have gone before us to test the many treatments and give the doctors the data to help predict for our best possible outcome.