It's a hard one, isn't it? I don't do sweet and pretty, either (hence the Amazon woman comment after my mastectomy) - tough and funny appeals to me more as it makes me feel more a doer than a done to. But would friends be game to buy boxes with those sort of sentiments? One of my closest friends would get it and my Mum if she was still around - I don't know if the others would. A choice might be the way but could add on too much expense or, find a balance between smart arse and sweet. I can't give you anything creative, though - brain's too scrambled for that and I haven't even started chemo!
I don't know: Radio - Grease Lightning; Chemo - It's Chemistry ...ugghh see what I mean.