HER2 negative now HER2 positive
Hi, I have had biopsies which showed hormone positive HER2 negative cancer. I had over 6 months of neoadjuvant chemo before bilateral mastectomy surgery and the results from the surgery shows my canc...
Forum Discussion
The biopsy from my initial diagnosis came back undecided, it was apparently in the middle so borderline for both. This then required an ISH test which came back negative. Apparently the ISH tests are more accurate.
After my surgeries my pathology came back -ve, I had ISH tests in both those.
On your pathology results there should be some figures and an explanation of what values determine whether +ve or -ve, they may help you understand.
I believe too that different laboratories can have slightly different perameters for deciding the HER value, but I am guessing that would only change it if you were close to the undecided value.
If you don't have copies of your pathology results, ask your surgeon or GP to print them out for you, you can then have a good look at them.
There is an excellent booklet you can download from www.breast cancer.org the main breast cancer site in the USA, it has a very detailed description of all the pathology results and what they mean, and spaces for you to write in your own.
After my surgeries my pathology came back -ve, I had ISH tests in both those.
On your pathology results there should be some figures and an explanation of what values determine whether +ve or -ve, they may help you understand.
I believe too that different laboratories can have slightly different perameters for deciding the HER value, but I am guessing that would only change it if you were close to the undecided value.
If you don't have copies of your pathology results, ask your surgeon or GP to print them out for you, you can then have a good look at them.
There is an excellent booklet you can download from www.breast cancer.org the main breast cancer site in the USA, it has a very detailed description of all the pathology results and what they mean, and spaces for you to write in your own.