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Mareealso's avatar
Mareealso
Member
13 hours ago

Exemstane and Nausea

Hi Everyone, Just wanting to know if anyone else has had severe nausea with Exemstane and if so, did it get better over time? I had my diagnosis, op and chemo 2023-2024 and was then placed on Arimidex. I then developed nausea and liver function tests showed higher levels, indicating that my liver was struggling. I was then taken off Arimidex and placed on Exemstane (2025) and after several months, am now having persistent nausea. Blood and Liver Function tests are normal however I am struggling with the “gastric” sides of things. I have just recently had to have  an iv of anti nausea medication in hospital plus an acid-reflux iv. I have been given tablets but was told that these are only for short term use. Any ideas?

treatment

1 Reply

  • arpie's avatar
    arpie
    Member
    1 hour ago

    I am so sorry you are having this side effect - strange that you had it with Arimidex as well as Exemestane! .... Nausea 'is' one of the side effects but I was lucky & didn't have it.  I was only on Arimidex for 6 months before swapping to Exemestane & was on that for over 6 years with no nausea, just the usual aches & pains.

    When do you take the tablets?  I used to take mine at night.  Can you change it to a different time & see if it gets better? 

    Do you take them before or after a meal?  Maybe Swap it around.

    Are you taking the 'actual' tablets, or one of the Pharmacy 'copies'?  Some of the copies use a different coating on the tablet - which might affect you adversely.

    Are you on anti-inflammatories at all?  I had a major liver function fail when I was put onto Mobic for a hip injury! My liver almost failed! 

    Have you had an 'uppie & downie' (colonoscopy/gastroscopy) in recent years (or ever had them??)  If this nausea persists, I think it would be wise to ask to have them done, to make sure there are no issues down there. 

    Acid reflux is often a problem associated with gut issues - and the tablets you are on only 'mask' the issue, it won't fix it.   :( 

    I've put a brick under both top legs of my bed, putting it on a very slight 'angle' (not enough to interrupt your sleeping) but enough to stop the stomach acid from going up into your throat!   I have regular uppies & downies too very 5 years.

    Take care & all the best xx