Tamoxifen & Thyroxine

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Life
Life Member Posts: 14
I’ve been on Thyroxine meds (under active thyroid) for years without issues, but now with taking Tamoxifen, it seems things are not the same. Doc wants to monitor me for a couple more months before she changes things. 
My questions are , anyone out there taking them together? Or should I separate them ? 
And if separated which should I take in the morning & which in the evening? Doc was not helpful at all. 
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  • kmakm
    kmakm Member Posts: 7,974
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    Interesting @Life. I've been taking thyroxine for 16 years (100mcg nightly). I'm on Letrozole (which I take in the morning) and there's been no issue at all. My TSH levels are holding steady. Would a switch to an AI be possible? K xox
  • Life
    Life Member Posts: 14
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    I’ve been taking them together in the morning, as pharmacist said it’s ok. But this week after doc appointment, have tried to split them with Tamoxifen in the morning & Thyroxine in the night , but have found I’m heading to bed & then I remember I’ve forgotten to take it. Easier for me to remember in the morning. Don’t know if I should keep trying to keep them separate or just take them in the morning together. Was wondering if anyone else does ? 
  • iserbrown
    iserbrown Member Posts: 5,552
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    Mine are morning as it is easier to remember.  Thyroxine at least half hour before breakfast. AI after breakfast so they are about an hour apart.

    When I was on tamoxifen I used to take it after my lunch mainly to manage side effects.

    Take care 
  • AllyJay
    AllyJay Member Posts: 945
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    I also take both in the morning. The thyroxine with my first cup of tea in the morning...as I open the fridge for the milk, I see the box. Then about an hour later, the rest of my morning meds, including the letrozole, straight after breakfast. I found when I took the thyroxine in the evening, with my night meds, I felt more jittery and experienced restless legs syndrome.
  • Life
    Life Member Posts: 14
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    thank you , I’ll try doing that. As night does not work for me , I keep forgetting. But the morning I have the time to take one as soon as I’m in the kitchen & then just before we head for the school run. 
  • JulieVT11
    JulieVT11 Member Posts: 90
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    I am taking thyroxine & T3 and tamoxifen.  I have the thyroid meds in my bathroom and take as soon as I get up then take my tamoxifen about hour or so later after breakfast and my levels have been very steady now for the last 12 months
  • primek
    primek Member Posts: 5,392
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    Are you taking any herbal things like tumeric also? This blocks thyroxine and should be taken at least 4 hours apart.
  • Life
    Life Member Posts: 14
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    Nothing herbal, just multi vitamins but at lunchtime. 
    I’ve been trying to take the thyroid meds when I get to the kitchen, in the morning & tamoxifen an hour later , before I leave. Hopefully this will be enough . I’ll find out in 2 mths. 
  • iserbrown
    iserbrown Member Posts: 5,552
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    Thyroxine should be taken 30 - 60 mins before food.