New study aimed at relieving hot flushes

Giovanna_BCNAGiovanna_BCNA Administrator, Staff, Member, Moderator Posts: 1,005
edited October 2018 in Community news and events

New study aimed at relieving hot flushes and night sweats experienced by women after breast cancer


Researchers in the Monash Women’s Health Research Program are conducting a study to evaluate a potential new treatment aimed at relieving hot flushes and night sweats in women diagnosed with breast cancer who are taking hormone blocking therapy (either tamoxifen or an aromatase inhibitor).


While clinical trials have found hormone blocking therapy can significantly reduce the risk of breast cancer coming back (recurring), many women experience menopausal-like symptoms when taking hormone-blocking therapy. While these side effects are mild for many women or lessen over time, some women experience significant symptoms which can be difficult to cope with.


The study will determine whether QUE 122 (a small molecule which was found to lessen hot flushes and night sweats in an earlier study) is effective in reducing night sweats and hot flushes in women affected by breast cancer being treated with hormone blocking therapy.


You may be eligible to participate if you are:

·         Aged 18 to 70 years

          Have been taking tamoxifen or an aromatase inhibitor (i.e. anastrozole (Arimidex), letrozole            (Femara) or exemestane (Aromasin) for at least 1 month

·         Are experiencing 7 or more hot flushes/night sweats each day.

This study is taking place at sites in Melbourne, Sydney, Adelaide and Perth.


If you are interested in participating or would like further information, please email [email protected] call Corallee on +61 3 9903 0836.


More information about the study is also available on the Women’s Health Research Program’s website.


For information about hormone blocking therapy, including how the drugs work, why they are beneficial and tips / strategies to help manage side effects, download BCNA’s Hormone therapy and breast cancer booklet on



  • arpiearpie Mid North Coast, NSWMember Posts: 2,704
    edited October 2018
    How good would it be if they could sort this problem out??

    @kmakm - this could be of interest to you?

  • Giovanna_BCNAGiovanna_BCNA Administrator, Staff, Member, Moderator Posts: 1,005
    Hello everyone,  please see link below

    Women wanting to express interest in participating in the clinical trial, can visit
  • Jane221Jane221 Central Coast, NSWMember Posts: 1,124
    This would have been such a great study to have been involved with a few years back when hot flushes and night sweats were almost constant for me. Thank god they've settled a lot now. Hope the trials finds some solutions, then hopefully more women might be able to stick with the hormone-blocking therapies. 
  • kmakmkmakm MelbourneMember Posts: 7,078
    I sent them an email yesterday morning but have not heard back from them. They've probably been inundated with desperate women... @arpie
  • arpiearpie Mid North Coast, NSWMember Posts: 2,704
    Cool!!  Only if they've seen/heard that the trial is on!!  We are lucky here on BCNA to have almost instantaneous news 'as it happens'!   :) 

    I hope you can get onto the trial, Kate.  I guess they'll want you to now document every one you have as well - before and after any treatment??
  • kmakmkmakm MelbourneMember Posts: 7,078
    @arpie I'll let you know if I'm accepted.
  • DoodooDoodoo Member Posts: 374
    Good luck @kmakm. So hope you get accepted. Everything crossed xx
  • [Deleted User][Deleted User] Posts: 79
    edited October 2018
    The user and all related content has been deleted.
  • lgray3911lgray3911 Member Posts: 206
    Omg I would love this! Night time is hell for me since treatment! 
  • The user and all related content has been deleted.
  • GlescagirlGlescagirl Member Posts: 5
    My Breast Care nurse told me of attending a recent conference where she heard that some women have used Acupuncture to gain relief from hot flushes. She is currently on leave, so I have been unable to find out more. Has anyone else heard of, or used this therapy.
  • kmakmkmakm MelbourneMember Posts: 7,078
    Hi @Glescagirl. You can use the search bar here to look up various threads about acupuncture. It comes up from time to time.

    I've looked into it, it's been studied a lot. As far as I can tell for hot flushes it's had mixed success. Some people have found it helps but others not. My oncologist looked it up for me once and was emphatic that there was no proof it helped.

    I've discussed it with my (new) oncologist who says there is some evidence that it helps with joint pain. I'm going to give it a go. If you do, let us know how you get on! K xox
  • EmieEmie Member Posts: 18
    @Glescagirl I have found acupuncture enormously beneficial to hot flushes - it hasn’t removed them entirely but they are much less severe and very manageable. I haven’t found it as helpful to the aches and pains however I am what the accupuncturists call a strong responder!
  • ElizebethElizebeth Member Posts: 80
    Hi Ladies..I do something called Bowen treatment for my hot flushes..try and find a good is a non invasive gentle process and after a few sessions I get relief...simple motions over the body to try and reregulste acupuncture minus the needles..whatever works..I recently started aromatise inhibitors having gone through menopause and hot flushes...only for them to start all over again! So back to Bowen I am’s not cheap but it helps me..
  • MoiraCMoiraC SydneyMember Posts: 166
    Hi all -I had six sessions of acupuncture but it didn't help my hot flushes sadly. I have been taking  the medication Cymbalta  prescribed by one of my drs for some months and has reduced my 4 sodden night sweats and daytime ones to 1or 2 a day.
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