Is anyone taking Anastrazole and Fulvestrant?

Mum_of_One

Hi Everyone,

I was diagnosed with de novo metastatic breast cancer in February this year. A 3.1cm lump in the breast and a 2.5cm liver lesion with 2 other small mets to the liver. I started on Anastrazole in February and had an ultrasound last week which showed the liver met down to 6 mm and the breast lump almost half the size it was. I don't feel very comfortable with my local oncologist and sought a second opinion in Sydney. The oncologist there mentioned combining Anastrazole and Fulvestrant to possibly give a longer period without disease progression. So now I'm not sure what to do!! I'm tolerating Anastrazole really well but would obviously I would like to maximise the time that the cancer does not progress. Does anyone take these 2 drugs together or have anything they can add to help with this decision? I've been checking in here regularly and admire you all, it's certainly a hard road to travel.

Thanks in advance for any information you can share.

primek

I don't have any personal knowledge but latest research seems to support this as being the best 1st line treatment.

Here is one link 

https://www.astrazeneca-us.com/media/press-releases/2016/fulvestrant-demonstrates-progression-free-survival-advantage-in-1st-line-advanced-breast-cancer-10082016.html

Kath x

Mum_of_One

Thanks for the response Kath. I think I've got some googling to do before my next appointment.

angg66

Hi @Mum_of_One. I have been on Fulvestrant now for around 5 months and it seems to be working in keeping my cancer stable. In fact my tumour markers have fallen since I've been getting these injections. I have mets in the bones in my back & in my right liver. Good luck with your decision.

Ang

Mum_of_One

Thanks for the information Ang. Here's hoping it keeps on working well for you.

socoda

Hi @Mum_of_One , can't help with this but just wanted to send you a hug. Xx 

Mum_of_One

Thanks Socoda. All hugs gratefully accepted.

KimW

all the best xx